Advanced Locking Plate System (ALPS®) Technology
anchored by KLS™
Overview
All KYON procedures and implants have been designed with an absolute focus on helping the surgeon to reduce the level of damage to blood perfusion and thus the risk of infection. Advanced Locking Plate System (ALPS®)* technology offers less iatrogenic trauma, greater versatility, increased overall stability, and early fracture healing advantages for animals.
ALPS-I, made commercially available in 2007, synthesized the key findings of KYON Founder, Slobodan Tepic, Dr. Sci., Dipl. Ing., who conducted the research and development on the PC-Fix (Point Contact Fixitor) in the 1980s and 1990s at the AO Research Institute, Davos, Switzerland, into a “biological internal fixation” system. “Biological internal fixation” involves the use of locked internal fixators, which have minimal implant-to-bone contact, long-span bridging, and fewer screws for fixation.[1]
In 2014, KYON Locking Screws (KLS™) technology, a novel thread design and locking mechanism, prohibited from inclusion in the ALPS-I due to PC-Fix patent restrictions, was combined with ALPS® technology. The screw direction is fixed for the larger screw diameter and can be angled through the plate by the use of a KLSTM bead and a 1 mm smaller diameter KYON Locking Screw. Designated compression holes within the plate allow for compression, also by KLS™ bead and screw. High stability and reliable load transfer of KLSTM allows for preferable use of mono-cortical screws where cortex thickness is sufficient to further protect the vascular supply.
In 2014 and 2015, KYON introduced KLS™ technology into clinical use in the Double Pelvic Osteotomy (ALPS® DPO) and Tibial Plateau Leveling Osteotomy (ALPS® TPLO) systems. In 2018, a KLS™ compatible version of the Proximal Abducting Ulnar Osteotomy (ALPS® PAUL-II) system entered clinical use. In 2019, ALPS® and KLS™ technology combine in ALPS-II.
As in ALPS-I, the shape of the ALPS-II plate allows for bending in both planes. The plate material is titanium; for the screws, titanium alloy. Finite Element Analysis was used to optimize the shape of the plate for the ideal balance of compliance and strength. Six sizes suitable for small animals, designated by the millimeter width of the plate (5, 6.5, 8, 9, 10 and 11 mm), are currently available. Plate contouring instruments from ALPS-I are compatible with ALPS-II.
Notes:
[1] – Perren SM, – Evolution of the internal fixation of long bone fractures. The scientific basis of biological internal fixation: choosing a new balance between stability and biology. J Bone Joint Surg Br. 2002 Nov;84(8): 1093-110.
BACKGROUND
The KYON Locking Screw (KLS)™ Innovation:
Publications:
Niederhäuser SK1, Tepic S2, Weber UT1.
Effect of screw position on single cycle to failure in bending and torsion of a locking plate–rod construct in a synthetic feline femoral gap model
American Journal of Veterinary Research. 2015 May; 76(2):402-410. doi: 10.2460/ajvr.76.5.402
1Tierärztliches Überweisungszentrum, Small Animal Referral Practice, CH-4456 Tenniken, Switzerland.
2Kyon AG, Technoparkstrasse 1, CH-8005 Zurich, Switzerland
Nojiri A1, Akiyoshi H, Ohashi F, Ijiri A, Sawase O, Matushita T, Takemoto M, Fujibayashi S, Nakamura T, Yamaguchi T1
Treatment of a unicameral bone cyst in a dog using a customized titanium device
J Vet Med Sci. 2015 Jan; 77(1): 127–131. doi: 10.1292/jvms.13-0548
1Fabre Animal Medical Center, 4–8 Minaminoguchi-cho, Kadoma, Osaka 571– 0065, Japan
Guerrero TG1, Kalchofner K, Scherrer N, Kircher P.
The Advanced Locking Plate System (ALPS): a retrospective evaluation in 71 small animal patients.
Vet Surg. 2014 Feb;43(2):127-35. doi: 10.1111/j.1532-950X.2014.12097.x. Epub 2014 Jan 6.
1Department for Small Animal Surgery, Vetsuisse Faculty University of Zurich, Zurich, Switzerland; Small Animal Medicine and Surgery Academic Program, School of Veterinary Medicine, St. George’s University, True Blue, Grenada, West Indies.
Pozzi A1, Peck JN, Chao P, Choate CJ, Barousse D, Conrad B.
Mechanical evaluation of adjunctive fixation for prevention of periprosthetic femur fracture with the Zurich cementless total hip prosthesis.
Vet Surg. 2013 Jun;42(5):529-34. doi: 10.1111/j.1532-950X.2013.12018.x. Epub 2013 Jun 3.
1Department of Small Animal Clinical Sciences, Comparative Orthopaedics and Biomechanics Laboratory, University of Florida, College of Veterinary Medicine, Gainesville, Florida, USA.
Blake CA1, Boudrieau RJ, Torrance BS, Tacvorian EK, Cabassu JB, Gaudette GR, Kowaleski MP.
Single cycle to failure in bending of three standard and five locking plates and plate constructs.
Vet Comp Orthop Traumatol. 2011;24(6):408-17. doi: 10.3415/VCOT-11-04-0061. Epub 2011 Sep 21.
1Department of Clinical Sciences, Tufts University, North Grafton, MA 01536, USA.
Cabassu JB1, Kowaleski MP, Skorinko JK, Blake CA, Gaudette GR, Boudrieau RJ.
Single cycle to failure in torsion of three standard and five locking plate constructs.
Vet Comp Orthop Traumatol. 2011;24(6):418-25. doi: 10.3415/VCOT-11-04-0050. Epub 2011 Sep 21.
1Department of Clinical Sciences, Tufts University, North Grafton, MA 01536, USA.
Inauen R1, Koch D, Bass M.
Arthrodesis of the tarsometatarsal joints in a cat with a two hole advanced locking plate system.
Vet Comp Orthop Traumatol. 2009;22(2):166-9.
1Koch&Bass Referal Practice for Small Animal Surgery, Basadingerstrasse 26, 8253 Diessenhofen, Switzerland. rinauen@kochbass.ch
Schlegel U1, Perren SM.
Surgical aspects of infection involving osteosynthesis implants: implant design and resistance to local infection.
Injury. 2006 May;37 Suppl 2:S67-73.
1AO Research Institute, AO Foundation, Davos, Switzerland. urs.schlegel@aofoundation.org
Perren SM.
Backgrounds of the technology of internal fixators.
Injury. 2003 Nov;34 Suppl 2:B1-3.
AO Research Institute, Davos, Switzerland.
Perren SM.
Evolution of the internal fixation of long bone fractures. The scientific basis of biological internal fixation: choosing a new balance between stability and biology.
J Bone Joint Surg Br. 2002 Nov;84(8):1093-110.
AO Research and Development Institutes, Davos, Switzerland.
Eijer H1, Hauke C, Arens S, Printzen G, Schlegel U, Perren SM.
PC-Fix and local infection resistance–influence of implant design on postoperative infection development, clinical and experimental results.
Injury. 2001 Sep;32 Suppl 2:B38-43.
1Department of Orthopaedic Surgery, University Hospital Amsterdam, The Netherlands. heijer@go.com
Hertel R1, Eijer H, Meisser A, Hauke C, Perren SM.
Biomechanical and biological considerations relating to the clinical use of the Point Contact-Fixator–evaluation of the device handling test in the treatment of diaphyseal fractures of the radius and/or ulna.
Injury. 2001 Sep;32 Suppl 2:B10-4.
1Department of Orthopaedic Surgery, Inselspitel, University Berne, Switzerland.
Haas N1, Hauke C, Schütz M, Kääb M, Perren SM.
Treatment of diaphyseal fractures of the forearm using the Point Contact Fixator (PC-Fix): results of 387 fractures of a prospective multicentric study (PC-Fix II).
Injury. 2001 Sep;32 Suppl 2:B51-62.
1Clinic for Trauma and Reconstructive Surgery, Charité, Humboldt University, Berlin, Germany.
Arens S1, Eijer H, Schlegel U, Printzen G, Perren SM, Hansis M.
Influence of the design for fixation implants on local infection: experimental study of dynamic compression plates versus point contact fixators in rabbits.
J Orthop Trauma. 1999 Sep-Oct;13(7):470-6.
1AO ASIF Research Institute, Davos, Switzerland.
Fernández Dell’Oca AA1, Tepic S, Frigg R, Meisser A, Haas N, Perren SM.
Treating forearm fractures using an internal fixator: a prospective study.
Clin Orthop Relat Res. 2001 Aug;(389):196-205.
1British Hospital, Montevideo, Uruguay.
Hauke C1, Meisser A, Perren SM.
Methodology of clinical trials focusing on the PC-Fix clinical trials.
Injury. 2001 Sep;32 Suppl 2:B26-37.
1AO ASIF Development Clinical Investigation, Davos-Platz, Switzerland. Christian.Hauke@hcuge.ch
Tepic S1, Remiger AR, Morikawa K, Predieri M, Perren SM.
Strength recovery in fractured sheep tibia treated with a plate or an internal fixator: an experimental study with a two-year follow-up.
J Orthop Trauma. 1997 Jan;11(1):14-23.
1Research Institute, AO/ASIF Foundation, Davos, Switzerland.
Arens S1, Hansis M, Schlegel U, Eijer H, Printzen G, Ziegler WJ, Perren SM.
Infection after open reduction and internal fixation with dynamic compression plates–clinical and experimental data.
Injury. 1996;27 Suppl 3:SC27-33.
1AO/ASIF Research Institute, Davos, Switzerland.
Ungersböck A1, Pohler OE, Perren SM.
Evaluation of soft tissue reactions at the interface of titanium limited contact dynamic compression plate implants with different surface treatments: an experimental sheep study.
Biomaterials. 1996 Apr;17(8):797-806.
1Department of Orthopaedic Surgery, University of Bern, Switzerland.
Miclau T1, Remiger A, Tepic S, Lindsey R, McIff T.
A mechanical comparison of the dynamic compression plate, limited contact-dynamic compression plate, and point contact fixator.
J Orthop Trauma. 1995 Feb;9(1):17-22.
1Department of Orthopedic Surgery, Baylor College of Medicine, Houston, TX 77030, USA.
Ungersböck A1, Pohler O, Perren SM.
Evaluation of the soft tissue interface at titanium implants with different surface treatments: experimental study on rabbits.
Biomed Mater Eng. 1994;4(4):317-25.
1AO/ASIF Research Institute Davos, Switzerland.
SYSTEM REVIEW
DOWNLOADS
ALPS Range Brochures: | Quotes, Pricelists and Training Opportunities: |
|---|---|
Comprehensive ALPS Range Booklet |  DOWNLOAD an excel pricelist and customize your system. |
ALPS-II Range | DOWNLOAD a folder of quotes for a complete and basic ALPS-II system as well as quotes for upgrading from ALPS-I to ALPS-II. |
TPLO Range | DOWNLOAD a folder of quotes for the complete TPLO range and a TPLO size 10 starter system. |
PAUL-II Range | DOWNLOAD a folder of quotes for the complete PAUL-II range and a PAUL-II starter system. |
DPO Range | DOWNLOAD a quote for a basic DPO system. |
Videos
Presentations:
Demonstrations:
The following video contain general instruction demonstrations, using ALPS-I. ALPS-II instructional videos will be available soon.
